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Description

Although primarily known as a pro-inflammatory cytokine that binds to cell membrane receptors to potentiate intracellular signaling 45 , eNAMPT can also be taken up by cells such as neurons and increase NAD + synthesis 46

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Oral administration has the benefit of high patient compliance and has demonstrated the potential to target brain iron pathology, especially with BBB-permeant agents like DFP

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